PHARMA DIVISION

TS Terminal Sterilizers

DESIGNED FOR

The Sterilizers type TS-AS & TS-OW are specifically designed for the Terminal Sterilization of liquids contained in sealed containers (plastic bags, glass bottles, BFS bottles, syringes, ampoules, etc.) as they are prepared to provide an automatic differential pressure compensation based on product probes (RTD) temperature measurement (ΔT). This kind of control prevent the deformation, damaging and bad coloring of the plastic containers.

PROCESS FEATURES

Pre-selected and custom made programs for any need. The machine process is developed by our Automation Department following the current codes/standards and type of product to be processed. Two are the methods/typology currently used: Terminal Sterilization using Air + Steam Mixture, machine type TS-AS These Sterilizers are fitted with an integrated ventilator system for mixing clean steam with air, which becomes the sterilization media. This process method should be recommended for complex plastic or glass containers such as pre-filled syringes or vials in which condensates may stagnant and be source of problems in the finish product. The system guarantees an excellent distribution of the heat during all sterilization phase (temperature deviation below ± 1 °C). These autoclaves also provide better drying finish thanks to the ventilator system and thus, products are downloaded ready for packing and labeling. Terminal Sterilization using Overheated Water, machine type TS-OW These Sterilizers are fitted with a high flow recirculation system by a sanitary pump and heat exchanger of multi-tubes double-heads type that allows using (WFI or Demi) water as heat transfer media for heating up, sterilizing and cooling down the load. The system guarantees an excellent distribution of the heat during all sterilization phase (temperature deviation below ± 1 °C). This process method provides faster cycles but containers come out damp. Anyhow, it is the preferred method in most cases due to its simplicity, economy and ease of validation.
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